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Patterns of mutations in TP53 mutated AML

TP53 mutated acute myeloid leukemia (AML) responds poorly to chemotherapy and has a short overall survival rate with a median of 5–9 months. Poor outcomes in TP53 mutated AML following chemotherapy have been observed and treatment options remain limited, although the presence of TP53 mutations alone...

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Detalhes bibliográficos
Publicado no:Best Pract Res Clin Haematol
Autor principal: Welch, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482955/
https://ncbi.nlm.nih.gov/pubmed/30466751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2018.09.010
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