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Desulfonative photoredox alkylation of N-heteroaryl sulfones – an acid-free approach for substituted heteroarene synthesis

Minisci-type alkylation of electron-deficient heteroarenes has been a pivotal technique for medicinal chemists in the synthesis of drug-like molecules. However, such transformations usually require harsh conditions (e.g., strong acids, stoichiometric amount of oxidants, elevated temperatures, etc.)....

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Wang, Zheng-Jun, Zheng, Shuai, Matsui, Jennifer K., Lu, Zhipeng, Molander, Gary A.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482881/
https://ncbi.nlm.nih.gov/pubmed/31057765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00776h
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