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Origin and bioactivities of thiosulfinated FK228

During a large laboratory-scale purification of FK228 from the fermentation broth of Burkholderia thailandensis MSMB43, a small amount of thiosulfinated FK228 (TS-FK228) was unexpectedly purified only after the broth was mixed with silica gel. Evidence supports the postulations that TS-FK228 was der...

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Publicado en:Medchemcomm
Autores principales: Liu, Xiangyang, Currens, Grant C., Xue, Liang, Cheng, Yi-Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482872/
https://ncbi.nlm.nih.gov/pubmed/31057733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00060g
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