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A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane
Na(+)-K(+)-2Cl(−) cotransporter-1 (NKCC1) mediates the electroneutral transport of Na(+), K(+), and Cl(−) and is normally localized to the basolateral membrane of polarized epithelial cells. We recently reported the first known solute carrier family 12 member 2 (SLC12A2) mutation (we call NKCC1-DFX)...
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| Publicado en: | Am J Physiol Cell Physiol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482672/ https://ncbi.nlm.nih.gov/pubmed/30865516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00023.2019 |
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