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A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane

Na(+)-K(+)-2Cl(−) cotransporter-1 (NKCC1) mediates the electroneutral transport of Na(+), K(+), and Cl(−) and is normally localized to the basolateral membrane of polarized epithelial cells. We recently reported the first known solute carrier family 12 member 2 (SLC12A2) mutation (we call NKCC1-DFX)...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Cell Physiol
Asıl Yazarlar: Koumangoye, Rainelli, Omer, Salma, Delpire, Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482672/
https://ncbi.nlm.nih.gov/pubmed/30865516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00023.2019
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