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Genetic and pharmacological inactivation of apical Na(+)-K(+)-2Cl(−) cotransporter 1 in choroid plexus epithelial cells reveals the physiological function of the cotransporter
Choroid plexus epithelial cells (CPECs) secrete cerebrospinal fluid (CSF). They express Na(+)-K(+)-ATPase and Na(+)-K(+)-2Cl(−) cotransporter 1 (NKCC1) on their apical membrane, deviating from typical basolateral membrane location in secretory epithelia. Given this peculiarity, the direction of basa...
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| Publicado no: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482671/ https://ncbi.nlm.nih.gov/pubmed/30576237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00026.2018 |
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