Na(+) deposition in the fibrotic skin of systemic sclerosis patients detected by (23)Na-magnetic resonance imaging

Objective. Skin fibrosis is the predominant feature of SSc and arises from excessive extracellular matrix deposition. Glycosaminoglycans are macromolecules of the extracellular matrix, which facilitate Na(+) accumulation in the skin. We used (23)Na-MRI to quantify Na(+) in skin. We hypothesized that...

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Udgivet i:Rheumatology (Oxford)
Main Authors: Kopp, Christoph, Beyer, Christian, Linz, Peter, Dahlmann, Anke, Hammon, Matthias, Jantsch, Jonathan, Neubert, Patrick, Rosenhauer, Daniela, Müller, Dominik N., Cavallaro, Alexander, Eckardt, Kai-Uwe, Schett, Georg, Luft, Friedrich C., Uder, Michael, Distler, Jörg H. W., Titze, Jens
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Clinical Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482592/
https://ncbi.nlm.nih.gov/pubmed/28013199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew371
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