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BRCA1 mRNA expression modifies the effect of T cell activation score on patient survival in breast cancer
BACKGROUND: Effector CD8(+) T cell activation and its cytotoxic function to eradicate tumor cells depend on the T cell recognition of tumor neoantigens, and are positively associated with improved survival in breast cancer. Tumor suppressor BRCA1 and cell cycle regulator CCND1 play a critical role i...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482542/ https://ncbi.nlm.nih.gov/pubmed/31023256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5595-3 |
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