ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway

BACKGROUND: Breast cancer angiogenesis is key for metastasis and predicts a poor prognosis. Angiotensin-converting enzyme 2 (ACE2), as a member of the renin-angiotensin system (RAS), was reported to restrain the progression of hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) thr...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Zhang, Qi, Lu, Sihong, Li, Tianfu, Yu, Liang, Zhang, Yunjian, Zeng, Huijuan, Qian, Xueke, Bi, Jiong, Lin, Ying
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482513/
https://ncbi.nlm.nih.gov/pubmed/31023337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1156-5
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