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Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of l-DOPA from d-glucose

BACKGROUND: Production of l-tyrosine is gaining grounds as the market size of 3,4-dihydroxyphenyl-l-alanine (l-DOPA) is expected to increase due to increasing cases of Parkinson’s disease a neurodegenerative disease. Attempts to overproduce l-tyrosine for conversion to l-DOPA has stemmed on the over...

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Publicado en:Microb Cell Fact
Autores principales: Fordjour, Eric, Adipah, Frederick Komla, Zhou, Shenghu, Du, Guocheng, Zhou, Jingwen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482505/
https://ncbi.nlm.nih.gov/pubmed/31023316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1122-0
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