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Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein

RNA virus high mutation rate is a double-edged sword. At the one side, most mutations jeopardize proteins functions; at the other side, mutations are needed to fuel adaptation. The relevant question then is the ratio between beneficial and deleterious mutations. To evaluate this ratio, we created a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol Evol
Hauptverfasser: González, Rubén, Wu, Beilei, Li, Xianghua, Martínez, Fernando, Elena, Santiago F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482416/
https://ncbi.nlm.nih.gov/pubmed/30918938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz069
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