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Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein

RNA virus high mutation rate is a double-edged sword. At the one side, most mutations jeopardize proteins functions; at the other side, mutations are needed to fuel adaptation. The relevant question then is the ratio between beneficial and deleterious mutations. To evaluate this ratio, we created a...

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書目詳細資料
發表在:Genome Biol Evol
Main Authors: González, Rubén, Wu, Beilei, Li, Xianghua, Martínez, Fernando, Elena, Santiago F
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482416/
https://ncbi.nlm.nih.gov/pubmed/30918938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz069
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