Nox2 NADPH oxidase is dispensable for platelet activation or arterial thrombosis in mice

Deficiency of the Nox2 (gp91phox) catalytic subunit of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is a genetic cause of X-linked chronic granulomatous disease, a condition in which patients are prone to infection resulting from the loss of oxidant production by neutrophils. Some stu...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Sonkar, Vijay K., Kumar, Rahul, Jensen, Melissa, Wagner, Brett A., Sharathkumar, Anjali A., Miller, Francis J., Fasano, MaryBeth, Lentz, Steven R., Buettner, Garry R., Dayal, Sanjana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482355/
https://ncbi.nlm.nih.gov/pubmed/30995985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018025569
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