Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats

Knee osteoarthritis (KOA) is associated with muscle weakness, but it is unclear which structures are involved in the muscle changes. This study assessed morphological alterations and the expression of genes and proteins linked to muscular atrophy and neuromuscular junctions (NMJs) in KOA, induced by...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Cunha, Jonathan Emanuel, Barbosa, Germanna Medeiros, Castro, Paula Aiello Tomé de Souza, Luiz, Beatriz Leite Ferreira, Silva, Andreza Cristine Arcari, Russo, Thiago Luiz, Vasilceac, Fernando Augusto, Cunha, Thiago Mattar, Cunha, Fernando Queiróz, Salvini, Tania Fátima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482306/
https://ncbi.nlm.nih.gov/pubmed/31019213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42546-7
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