TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter

TonEBP is a key transcriptional activator in macrophages with an M1 phenotype. High expression of TonEBP is associated with many inflammatory diseases. Heme oxygenase-1 (HO-1), a stress-inducible protein, is induced by various oxidative and inflammatory signals, and its expression is regarded as an...

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Pubblicato in:Front Immunol
Autori principali: Yoo, Eun Jin, Lee, Hwan Hee, Ye, Byeong Jin, Lee, Jun Ho, Lee, Chae Young, Kang, Hyun Je, Jeong, Gyu Won, Park, Hyun, Lim, Sun Woo, Lee-Kwon, Whaseon, Kwon, Hyug Moo, Choi, Soo Youn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482272/
https://ncbi.nlm.nih.gov/pubmed/31057560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00850
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