The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype

Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs is yet unknown. Our goal was to examine gene transcription by B. burgdorferi following doxycycline treatment in an effort...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Caskey, John R., Hasenkampf, Nicole R., Martin, Dale S., Chouljenko, Vladimir N., Subramanian, Ramesh, Cheslock, Mercedes A., Embers, Monica E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482230/
https://ncbi.nlm.nih.gov/pubmed/31057493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00690
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