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SAX-HPLC and HSQC NMR Spectroscopy: Orthogonal Methods for Characterizing Heparin Batches Composition

Heparin is a complex mixture of heterogeneous sulfated polysaccharidic chains. Its physico-chemical characterization is based on the contribution of several methods, but advantages of the use of complementary techniques have not been fully investigated yet. Strong-Anion-Exchange HPLC after enzymatic...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Spelta, Franco, Liverani, Lino, Peluso, Alessandra, Marinozzi, Maria, Urso, Elena, Guerrini, Marco, Naggi, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482219/
https://ncbi.nlm.nih.gov/pubmed/31058155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00078
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