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Potential for Thermal Damage to the Blood-Brain Barrier during Craniotomy Procedure: Implications for Intracortical Recording Microelectrodes

OBJECTIVE: Our objective was to determine how readily blood-brain barrier (BBB) disruption occurred as a result of bone drilling during a craniotomy to implant microelectrodes in rat cortex. While the phenomenon of heat production during bone-drilling is well-known, practices to evade damage to the...

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Detalhes bibliográficos
Publicado no:J Neural Eng
Main Authors: Shoffstall, Andrew J., Paiz, Jen, Miller, David, Rial, Griffin, Willis, Mitchell, Menendez, Dhariyat, Hostler, Stephen, Capadona, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482047/
https://ncbi.nlm.nih.gov/pubmed/29205169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1741-2552/aa9f32
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