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Fine-tuning of noise in gene expression with nucleosome remodeling

Engineering stochastic fluctuations of gene expression (or “noise”) is integral to precisely bias cellular-fate decisions and statistical phenotypes in both single-cell and multi-cellular systems. Epigenetic regulation has been shown to constitute a large source of noise, and thus, engineering stoch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:APL Bioeng
Hauptverfasser: Megaridis, Melina R., Lu, Yiyang, Tevonian, Erin N., Junger, Kendall M., Moy, Jennifer M., Bohn-Wippert, Kathrin, Dar, Roy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AIP Publishing LLC 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481717/
https://ncbi.nlm.nih.gov/pubmed/31069303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5021183
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