Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle

The major objective of this study was to understand the molecular basis of how sarcolipin uncoupling of SERCA regulates muscle oxidative metabolism. Using genetically engineered sarcolipin (SLN) mouse models and primary muscle cells, we demonstrate that SLN plays a crucial role in mitochondrial biog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Maurya, Santosh K., Herrera, Jose L., Sahoo, Sanjaya K., Reis, Felipe C.G., Vega, Rick B., Kelly, Daniel P., Periasamy, Muthu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481681/
https://ncbi.nlm.nih.gov/pubmed/30208317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.036
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