Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle

The major objective of this study was to understand the molecular basis of how sarcolipin uncoupling of SERCA regulates muscle oxidative metabolism. Using genetically engineered sarcolipin (SLN) mouse models and primary muscle cells, we demonstrate that SLN plays a crucial role in mitochondrial biog...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Maurya, Santosh K., Herrera, Jose L., Sahoo, Sanjaya K., Reis, Felipe C.G., Vega, Rick B., Kelly, Daniel P., Periasamy, Muthu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481681/
https://ncbi.nlm.nih.gov/pubmed/30208317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.036
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