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Infection drives meningeal engraftment by inflammatory monocytes that impairs CNS immunity

Tissue macrophages have an embryonic origin and can be replenished in some tissues under steady state conditions by blood monocytes. However, little is known about the residency and properties of infiltrating monocytes after an inflammatory challenge. The meninges of the central nervous system (CNS)...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Rua, Rejane, Lee, Jane Y., Silva, Alexander B., Swafford, Isabella S., Maric, Dragan, Johnson, Kory R., McGavern, Dorian B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481670/
https://ncbi.nlm.nih.gov/pubmed/30886419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0344-y
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