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Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells

Vitamin K serves as an essential co-factor in the γ-carboxylation of glutamate to γ-carboxyglutamate (GLA), a post-translational modification mediated by gamma-glutamyl carboxylase (GGCX) and vitamin K oxidoreductases (VKORC1 or VKORC1L1). While both phylloquinone (K1) and menaquinone (K2) support t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Beaudin, Sarah, Kokabee, Leila, Welsh, JoEllen
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481349/
https://ncbi.nlm.nih.gov/pubmed/31040920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26765
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