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Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

The bone marrow (BM) microenvironment plays a crucial role in the maintenance and regeneration of hematopoietic stem (HSC) and progenitor cells (HSPC). In particular, the vascular niche is responsible for regulating HSC maintenance, differentiation, and migration of cells in and out of the BM. Damag...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cary, Lynnette, Noutai, Daniel, Salber, Rudolph, Fadiyimu, Opeyemi, Gross, Arthur, Almeida-Porada, Graca, Kidane, Yared, Whitnall, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480930/
https://ncbi.nlm.nih.gov/pubmed/30978983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071795
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