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Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

The bone marrow (BM) microenvironment plays a crucial role in the maintenance and regeneration of hematopoietic stem (HSC) and progenitor cells (HSPC). In particular, the vascular niche is responsible for regulating HSC maintenance, differentiation, and migration of cells in and out of the BM. Damag...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Cary, Lynnette, Noutai, Daniel, Salber, Rudolph, Fadiyimu, Opeyemi, Gross, Arthur, Almeida-Porada, Graca, Kidane, Yared, Whitnall, Mark
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480930/
https://ncbi.nlm.nih.gov/pubmed/30978983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071795
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