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Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

The bone marrow (BM) microenvironment plays a crucial role in the maintenance and regeneration of hematopoietic stem (HSC) and progenitor cells (HSPC). In particular, the vascular niche is responsible for regulating HSC maintenance, differentiation, and migration of cells in and out of the BM. Damag...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Cary, Lynnette, Noutai, Daniel, Salber, Rudolph, Fadiyimu, Opeyemi, Gross, Arthur, Almeida-Porada, Graca, Kidane, Yared, Whitnall, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480930/
https://ncbi.nlm.nih.gov/pubmed/30978983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071795
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