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Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies

BACKGROUND: The circadian clock governs a large variety of fundamentally important physiological processes in all three domains of life. Consequently, asynchrony in timekeeping mechanisms could give rise to cellular dysfunction underpinning many disease pathologies including human neoplasms. Yet, de...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Chang, Wai Hoong, Lai, Alvina G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480786/
https://ncbi.nlm.nih.gov/pubmed/31014368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1880-9
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