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Intratumoral heterogeneity of EGFR-activating mutations in advanced NSCLC patients at the single-cell level

BACKGROUND: Intratumoral epidermal growth factor receptor (EGFR) mutational heterogeneity is yet controversial in non-small cell lung cancer (NSCLC) patients. Single-cell analysis provides the genetic profile of single cancer cells and an in-depth understanding of the heterogeneity of a tumor. METHO...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Guo, Longhua, Chen, Zhihong, Xu, Chongrui, Zhang, Xuchao, Yan, Honghong, Su, Jian, Yang, Jinji, Xie, Zhi, Guo, Weibang, Li, Feng, Wu, Yilong, Zhou, Qing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480785/
https://ncbi.nlm.nih.gov/pubmed/31014278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5555-y
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