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Treatment and monitoring of Philadelphia chromosome-positive leukemia patients: recent advances and remaining challenges

The Philadelphia (Ph) chromosome, resulting from the t(9;22)(q34;q11) translocation, can be found in chronic myeloid leukemia (CML) as well as in a subset of acute lymphoblastic leukemias (ALL). The deregulated BCR-ABL1 tyrosine kinase encoded by the fusion gene resulting from the translocation is c...

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Pubblicato in:J Hematol Oncol
Autori principali: Soverini, Simona, Bassan, Renato, Lion, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480772/
https://ncbi.nlm.nih.gov/pubmed/31014376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0729-2
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