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Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age

Ras homolog enriched in striatum (Rhes) is a protein that exerts important physiological functions and modulates psychostimulant drug effects. On this basis, the object of this study was to assess 3,4-methylenedioxymethamphetamine (MDMA) effects on microglial (CD11b) and astroglial (GFAP) activation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Costa, Giulia, Porceddu, Pier Francesca, Serra, Marcello, Casu, Maria Antonietta, Schiano, Valentina, Napolitano, Francesco, Pinna, Annalisa, Usiello, Alessandro, Morelli, Micaela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480667/
https://ncbi.nlm.nih.gov/pubmed/30925704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071556
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