Elucidation of Novel Therapeutic Targets for Acute Myeloid Leukemias with RUNX1-RUNX1T1 Fusion

The RUNX1-RUNX1T1 fusion is a frequent chromosomal alteration in acute myeloid leukemias (AMLs). Although RUNX1-RUNX1T1 fusion protein has pivotal roles in the development of AMLs with the fusion, RUNX1-RUNX1T1, fusion protein is difficult to target, as it lacks kinase activities. Here, we used bioi...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Yun, Jae Won, Bae, Yoon Kyung, Cho, So Yeong, Koo, Harim, Kim, Hee-Jin, Nam, Do-Hyun, Kim, Sun-Hee, Chun, Sejong, Joo, Kyeung Min, Park, Woong-Yang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480444/
https://ncbi.nlm.nih.gov/pubmed/30959925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071717
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