Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study

An efficient and practical method for the synthesis of 2,6-diaryl-4-oxo-N,N′-di(pyridin-2-yl)cyclohexane-1,1-dicarboxamide is described in this present study, which occurs through a double Michael addition reaction between diamide and various dibenzalacetones. The reaction was carried out in dichlor...

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Bibliographic Details
Published in:Molecules
Main Authors: Al-Majid, Abdullah Mohammed, Islam, Mohammad Shahidul, Atef, Saleh, El-Senduny, Fardous F., Badria, Farid A., Elshaier, Yaseen A. M. M., Ali, M., Barakat, Assem, Motiur Rahman, A. F. M.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480224/
https://ncbi.nlm.nih.gov/pubmed/30987350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071332
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