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The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases
Activated protein C (APC) is a vitamin-K dependent plasma serine protease, which functions as a natural anticoagulant to downregulate thrombin generation in the clotting cascade. APC also modulates cellular homeostasis by exhibiting potent cytoprotective and anti-inflammatory signaling activities. T...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479968/ https://ncbi.nlm.nih.gov/pubmed/30974752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071762 |
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