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Ion Channels Involved in Substance P-Mediated Nociception and Antinociception

Substance P (SP), an 11-amino-acid neuropeptide, has long been considered an effector of pain. However, accumulating studies have proposed a paradoxical role of SP in anti-nociception. Here, we review studies of SP-mediated nociception and anti-nociception in terms of peptide features, SP-modulated...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chang, Chu-Ting, Jiang, Bo-Yang, Chen, Chih-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479580/
https://ncbi.nlm.nih.gov/pubmed/30935032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071596
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