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New Quinoline-Based Heterocycles as Anticancer Agents Targeting Bcl-2
The Bcl-2 protein has been studied as an anticancer drug target in recent years, due to its gatekeeper role in resisting programmed cancer cell death (apoptosis), and the design of BH3 domain mimetics has led to the clinical approval of Venetoclax (ABT-199) for the treatment of chronic lymphocytic l...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479519/ https://ncbi.nlm.nih.gov/pubmed/30986908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071274 |
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