Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity

We report the design, synthesis, and in vitro antimicrobial activity of a series of N-substituted 3-aminopyrazine-2-carboxamides with free amino groups in position 3 on the pyrazine ring. Based on various substituents on the carboxamidic moiety, the series is subdivided into benzyl, alkyl, and pheny...

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Bibliographic Details
Published in:Molecules
Main Authors: Bouz, Ghada, Semelková, Lucia, Janďourek, Ondřej, Konečná, Klára, Paterová, Pavla, Navrátilová, Lucie, Kubíček, Vladimír, Kuneš, Jiří, Doležal, Martin, Zitko, Jan
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479349/
https://ncbi.nlm.nih.gov/pubmed/30925695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071212
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