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Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors

Recent studies have demonstrated that human neutrophil elastase (HNE) can be used as marker for inflammation/infection of chronic wounds since it was found to be present in high concentration in exudate collected from chronic wounds. Biosensors used in wound care benefit from a chromogenic signallin...

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Publicat a:Biotechnol Rep (Amst)
Autors principals: Ferreira, Ana V., Antunes, Egipto, Ribeiro, Artur, Matamá, Teresa, Azoia, Nuno G., Cunha, Joana, Cavaco-Paulo, Artur
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479270/
https://ncbi.nlm.nih.gov/pubmed/31049301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2019.e00324
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