Nonparenchymal fluid is the source of increased mean diffusivity in preclinical Alzheimer's disease

INTRODUCTION: Although increased mean diffusivity of the white matter has been repeatedly linked to Alzheimer’s disease pathology, the underlying mechanism is not known. METHODS: Here, we used ADNI-3 multishell diffusion magnetic resonance imaging data to separate the diffusion signal of the parench...

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Dement (Amst)
Hauptverfasser: Sepehrband, Farshid, Cabeen, Ryan P., Barisano, Giuseppe, Sheikh-Bahaei, Nasim, Choupan, Jeiran, Law, Meng, Toga, Arthur W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Neuroimaging
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479267/
https://ncbi.nlm.nih.gov/pubmed/31049392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.03.002
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