DNA i-Motifs With Guanidino-i-Clamp Residues: The Counterplay Between Kinetics and Thermodynamics and Implications for the Design of pH Sensors

I-motif structures, adopted by cytosine-rich DNA strands, have attracted considerable interest as possible regulatory elements in genomes. Applied science exploits the advantages of i-motif stabilization under acidic conditions: i-motif-based pH sensors and other biocompatible nanodevices are being...

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Vydáno v:Comput Struct Biotechnol J
Hlavní autoři: Tsvetkov, Vladimir B., Zatsepin, Timofei S., Turaev, Anton V., Farzan, Valentina M., Pozmogova, Galina E., Aralov, Andrey V., Varizhuk, Anna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Network of Computational and Structural Biotechnology 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479070/
https://ncbi.nlm.nih.gov/pubmed/31049164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.04.006
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