RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point

The cellular decision regarding whether to undergo proliferation or death is made at the restriction (R)-point, which is disrupted in nearly all tumors. The identity of the molecular mechanisms that govern the R-point decision is one of the fundamental issues in cell biology. We found that early aft...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Lee, Jung-Won, Kim, Da-Mi, Jang, Ju-Won, Park, Tae-Geun, Song, Soo-Hyun, Lee, You-Soub, Chi, Xin-Zi, Park, Il Yeong, Hyun, Jin-Won, Ito, Yoshiaki, Bae, Suk-Chul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479060/
https://ncbi.nlm.nih.gov/pubmed/31015486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09810-w
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