A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection

Coagulation and inflammation are interconnected, suggesting that coagulation plays a key role in the inflammatory response to pathogens. A phenome-wide association study (PheWAS) was used to identify clinical phenotypes of patients with a polymorphism in coagulation factor X. Patients with this sing...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Choby, Jacob E., Monteith, Andrew J., Himmel, Lauren E., Margaritis, Paris, Shirey-Rice, Jana K., Pruijssers, Andrea, Jerome, Rebecca N., Pulley, Jill, Skaar, Eric P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479028/
https://ncbi.nlm.nih.gov/pubmed/30782860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00031-19
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