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Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis
Asp-Glu-Ala-Asp (DEAD)-box polypeptide 3 X-linked (DDX3X) is an ATP-dependent RNA helicase, In addition to involvement of eukaryotic gene expression regulation, mammalian DDX3X has recently been found to regulate IFN-β production via the adaptor MAVS mediated cascade signaling. In our studies, we de...
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| Veröffentlicht in: | Front Immunol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478769/ https://ncbi.nlm.nih.gov/pubmed/31057547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00822 |
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