Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development

The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in zebrafish are composed of segment populations that have unique absorptive and secretory roles, as well as multiciliated cells (MCCs) that govern fluid flow. Here, we report that the...

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Udgivet i:Sci Rep
Main Authors: Marra, Amanda N., Cheng, Christina N., Adeeb, Basma, Addiego, Amanda, Wesselman, Hannah M., Chambers, Brooke E., Chambers, Joseph M., Wingert, Rebecca A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478698/
https://ncbi.nlm.nih.gov/pubmed/31015532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42943-y
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