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Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development

The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in zebrafish are composed of segment populations that have unique absorptive and secretory roles, as well as multiciliated cells (MCCs) that govern fluid flow. Here, we report that the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marra, Amanda N., Cheng, Christina N., Adeeb, Basma, Addiego, Amanda, Wesselman, Hannah M., Chambers, Brooke E., Chambers, Joseph M., Wingert, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478698/
https://ncbi.nlm.nih.gov/pubmed/31015532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42943-y
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