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Nuclear membrane protein Lem2 regulates nuclear size through membrane flow

The size of the membrane-bound nucleus scales with cell size in a wide range of cell types but the mechanisms determining overall nuclear size remain largely unknown. Here we investigate the role of fission yeast inner nuclear membrane proteins in determining nuclear size, and propose that the Lap2-...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kume, Kazunori, Cantwell, Helena, Burrell, Alana, Nurse, Paul
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478680/
https://ncbi.nlm.nih.gov/pubmed/31015410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09623-x
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