Mutations in the SPAST gene causing hereditary spastic paraplegia are related to global topological alterations in brain functional networks

AIM: Our aim was to describe the rearrangements of the brain activity related to genetic mutations in the SPAST gene. METHODS: Ten SPG4 patients and ten controls underwent a 5 min resting state magnetoencephalography recording and neurological examination. A beamformer algorithm reconstructed the ac...

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Veröffentlicht in:Neurol Sci
Hauptverfasser: Rucco, Rosaria, Liparoti, Marianna, Jacini, Francesca, Baselice, Fabio, Antenora, Antonella, De Michele, Giuseppe, Criscuolo, Chiara, Vettoliere, Antonio, Mandolesi, Laura, Sorrentino, Giuseppe, Sorrentino, Pierpaolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478644/
https://ncbi.nlm.nih.gov/pubmed/30737580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10072-019-3725-y
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