The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

In rodent models of type 2 diabetes (T2D), sustained remission of diabetic hyperglycemia can be induced by a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1). To identify the brain areas responsible for this effect, we first used immunohistochemistry to map the hyp...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Brown, Jenny M., Scarlett, Jarrad M., Matsen, Miles E., Nguyen, Hong T., Secher, Anna, Jorgensen, Rasmus, Morton, Gregory J., Schwartz, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477902/
https://ncbi.nlm.nih.gov/pubmed/30796029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0025
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