Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

Throughout metazoans, Staufen (Stau) proteins are core factors of mRNA localization particles. They consist of three to four double-stranded RNA binding domains (dsRBDs) and a C-terminal dsRBD-like domain. Mouse Staufen2 (mStau2)-like Drosophila Stau (dmStau) contains four dsRBDs. Existing data sugg...

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Publicado no:Nat Commun
Main Authors: Heber, Simone, Gáspár, Imre, Tants, Jan-Niklas, Günther, Johannes, Moya, Sandra M. Fernandez, Janowski, Robert, Ephrussi, Anne, Sattler, Michael, Niessing, Dierk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477676/
https://ncbi.nlm.nih.gov/pubmed/30971701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09655-3
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