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Protection of Kidney Function with Human Antioxidation Protein α(1)-Microglobulin in a Mouse (177)Lu-DOTATATE Radiation Therapy Model

Aims: Peptide receptor radionuclide therapy (PRRT) is in clinical use today to treat metastatic neuroendocrine tumors. Infused, radiolabeled, somatostatin analog peptides target tumors that are killed by irradiation damage. The peptides, however, are also retained in kidneys due to glomerular filtra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antioxid Redox Signal
Hauptverfasser: Kristiansson, Amanda, Ahlstedt, Jonas, Holmqvist, Bo, Brinte, Anders, Tran, Thuy A., Forssell-Aronsson, Eva, Strand, Sven-Erik, Gram, Magnus, Åkerström, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477591/
https://ncbi.nlm.nih.gov/pubmed/29943622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7517
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