Safety and tolerability of subcutaneous sarilumab and intravenous tocilizumab in patients with rheumatoid arthritis

OBJECTIVE: Safety and efficacy of mAbs blocking the IL-6 receptor have been established in RA. This is the first analysis examining safety and tolerability of sarilumab and tocilizumab administered as single or multiple doses in patients with RA within the same study. METHODS: In ASCERTAIN, patients...

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Vydáno v:Rheumatology (Oxford)
Hlavní autoři: Emery, Paul, Rondon, Juan, Parrino, Janie, Lin, Yong, Pena-Rossi, Claudia, van Hoogstraten, Hubert, Graham, Neil M H, Liu, Nancy, Paccaly, Anne, Wu, Richard, Spindler, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Clinical Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477522/
https://ncbi.nlm.nih.gov/pubmed/30590833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key361
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