Non-canonical Notch Signaling Regulates Actin Remodeling in Cell Migration by Activating PI3K/AKT/Cdc42 Pathway

Tumor cell migration is a critical step in cancer metastasis. Over-activated Notch pathway can promote the migration of cancer cells, especially in the breast cancer. However, the underlying mechanism of non-canonical Notch signaling in modulating the migration has not yet been clearly characterized...

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Udgivet i:Front Pharmacol
Main Authors: Liu, Lei, Zhang, Lin, Zhao, Shuo, Zhao, Xu-Yang, Min, Peng-Xiang, Ma, Ya-Dong, Wang, Yue-Yuan, Chen, Yan, Tang, Si-Jie, Zhang, Yu-Jie, Du, Jun, Gu, Luo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477508/
https://ncbi.nlm.nih.gov/pubmed/31057403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00370
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