IMMU-08. UNLOCKING CANCER IMMUNOTHERAPY AGAINST PEDIATRIC BRAIN TUMORS WITH TRANSCRIPTOME LOADED NANOPARTICLES

BACKGROUND: Pediatric brain tumors are poorly immunogenic preventing current immunotherapies (i.e. checkpoint blockers) from having significant activity. Unlocking immunotherapy against these malignancies is predicated on reprogramming their immunogenicity. OBJECTIVE/METHODS: We developed a novel tr...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Sayour, Elias, Gururangan, Sridharan, Stover, Brian, Grippin, Adam, McGuiness, James, Weidert, Frances, Deleyrolle, Loic, Sahay, Bikash, Carrera-Justiz, Sheila, Mendez-Gomez, Hector, Mitchell, Duane
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Immunology/Immunotherapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477442/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.129
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