TMOD-05. C-MYC OVEREXPRESSION INDUCES CHOROID PLEXUS PAPILLOMAS THROUGH A T-CELL MEDIATED INFLAMMATORY MECHANISM

Choroid plexus tumours (CPTs) account for up to 20% of brain tumours in children under 2 years of age. They can spread along the neuraxis and can recur after treatment. Little is known about the molecular mechanisms underlying their formation and only few high fidelity mouse models of p53-deficient...

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Publicado en:Neuro Oncol
Autores principales: Merve, Ashirwad, Zhang, Xinyu, Pomella, Nicola, Dumas, Anaelle, Marino, Silvia
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Pediatric Brain Tumor Models
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477397/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.244
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