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HGG-15. SUCCESSFUL TREATMENT OF AN NTRK-FUSION POSITIVE INFANTILE GLIOBLASTOMA WITH LAROTRECTINIB, A TARGETED TRK INHIBITOR
PURPOSE: Targeted inhibition of NTRK-fusion proteins has shown promise in treatment of infantile fibrosarcoma in a phase 1 open-label study. Herein we report successful treatment of an NTRK-driven infantile glioblastoma with larotrectinib, a small molecule TRK inhibitor. RESULTS: A 2-month-old term...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477323/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.109 |
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