DIPG-04. TRANSLATION OF DNX-2401 FROM THE BENCH TO THE CLINIC FOR PEDIATRIC HIGH GRADE GLIOMAS INCLUDING DIFFUSE INTRINSIC PONTINE GLIOMAS

Despite our increased understanding of the genetic make-up and new therapies for pediatric high grade glioma (pHGG) and Diffuse Intrinsic Pontine Glioma (DIPG) the outcome remains grim. Delta-24-RGD (DNX-2401 in the clinic) has been tested for adult glioblastoma presenting a safe profile and promisi...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Martinez-Velez, Naiara, Garcia-Moure, Marc, Laspidea, Virginia, Becher, Oren, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño, Ana, Diez-Valle, Ricardo, Tejada-Solis, Sonia, Alonso, Marta
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Diffuse Intrinsic Pontine Glioma (DIPG)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477258/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.025
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