IMMU-12. NOVEL APPROACH FOR THE TREATMENT OF PEDIATRIC HIGH-GRADE GLIOMAS WITH THE COMBINATION OF ONCOLYTIC ADENOVIRUSES AND GENE THERAPY ENCODING A BiTE DIRECTED TO THE EphA2 TUMOR ANTIGEN.

Pediatric high-grade gliomas (pHGG) are amongst the most common malignant neoplasms of childhood, whose outcome remains dismal with conventional treatments. New therapeutic approaches are urgently needed. Immunotherapy based on Oncolytic Adenovirus(OA)is a promising strategy but its efficacy is subo...

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Publicado en:Neuro Oncol
Autores principales: Arnone, Claudia Manuela, Belardinilli, Tamascia, Mastronuzzi, Angela, Polito, Vinicia, Cacchione, Antonella, Carai, Andrea, Camassei, Francesca Diomedi, Scarsella, Marco, Quintarelli, Concetta, Angelis, Biagio De, Locatelli, Franco, Caruana, Ignazio, Del Bufalo, Francesca
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Immunology/Immunotherapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477208/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.133
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